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苏州赛默医学检验实验室是苏州精准医疗科技有限公司的全资子公司。苏州精准医疗科技有限公司所有的研究知识产权，包括发明专利、实用新型专利、发表的文章等均依托苏州赛默医学检验实验室进行。苏州精准医疗科技有限公司名下的所有的知识产权成果均由两家公司共同享有。
髓系肉瘤“侵润”去分化脂肪肉瘤：一种罕见的碰撞瘤，文章发表在British Journal of Haematology.
2026 Aug 28. doi: 10.1111/bjh.70744.
Myeloid Sarcoma “Invading” a Dedifferentiated Liposarcoma: A Rare Collision Tumor.
t(2;11)(p21;q23)导致CAMKMT基因组破坏并揭示急性髓系白血病中的糖酵解重编程机制，文章发表在Current Medicinal Chemistry.
2026 Jul 17. doi: 10.2174/0109298673437239260603062329.
Genomic Disruption of CAMKMT by t(2;11)(p21;q23) Reveals a Glycolytic Reprogramming Mechanism in Acute Myeloid Leukemia.
江苏大学附属人民医院血液科等①与苏州大学一苏州精准肿瘤分子病理研究院②合作报道了一例病例报告:通过RNA测序在一例骨髓增生异常肿瘤伴SF3B1突变患者中鉴定出罕见的细胞遗传学隐匿性MECOM重排，文章发表在Frontiers in Oncology.
2026 Jan 19;16:1742267. doi: 10.3389/fonc.2026.1742267.
A Rare Cytogenetically Cryptic MECOM Rearrangement in a Patient with Myelodysplastic Neoplasm and SF3B1 mutation Identified by RNA Sequencing: a Case report.
靶向RNA NGS辅助诊断2例AMKL，文章发表在中国小儿血液与肿瘤杂志。
2026年2月第31卷第1期，doi: 10. 3969 / j. issn. 1673 - 5323. 2026. 01. 013。
靶向RNA NGS辅助诊断2例AMKL
苏州大学附属第二医院血液科等①与苏州大学一苏州精准肿瘤分子病理研究院②合作报道了一篇血液和脑脊液循环肿瘤DNA在弥漫性大B细胞淋巴瘤(DLBCL)中的应用:同时分析基因突变、免疫球蛋白(IG)重排与克隆性重组，文章发表在British Journal of Cancer.
2025 Dec;133(12):1907-1915. doi: 10.1038/s41416-025-03217-9.
Circulating tumor DNA from blood and cerebrospinal fluid in DLBCL: simultaneous evaluation of mutations, lG rearrangement, and IG clonality.
病例报告：原发性髓外浆细胞瘤的分子与免疫学特征——新型IGH::NFKB1融合的发现及其对疾病进展和治疗的影响，文章发表在Frontiers in Immunology.
2025 Oct 22;16:1664103. doi: 10.3389/fimmu.2025.1664103.
Case Report: Molecular and immunological insights into primary extramedullary plasmacytoma: discovery of a novel IGH::NFKB1 fusion and its impact on disease progression and treatment.
NF-κB通路激活性突变与弥漫性大B细胞淋巴瘤中CpG刺激核型分析失败相关，文章发表在International Journal of Laboratory Hematology.
2026 Oct;48(5):1231-1235. doi: 10.1111/ijlh.70122.
NF-κB Pathway Activation Mutations Linked to Failure of CpG-Stimulated Karyotyping in DLBCL.
昆山市第一人民医院血液科等①与苏州精准医疗②合作报道了一例RUNX1:RUNX1T1 AML伴随KMT2A重排假阳性:FISH判读陷阱，文章发表在Hematology.
2024 Dec;29(1):2420306. doi: 10.1080/16078454.2024.2420306.
A RUNX1::RUNX1T1 AML with a Simultaneous False Positive KMT2A Rearrangement: FISH Interpretation Pitfalls.
苏州大学附属儿童医院血液科等①与苏州大学一苏州精准肿瘤分子病理研究院②合作报道了一篇儿童急性B淋巴细胞白血病中频繁的TCR重排:基因组和表型特征，文章发表在Annals of Hematology.
2025 Oct;104(10):5283-5295. doi: 10.1007/s00277-025-06687-2.
Frequent TCR rearrangements in pediatric B-cell lymphoblastic acute leukemia: genomic and phenotypic features.
苏州大学附属儿童医院儿科重症监护室等①与苏州大学一苏州精准肿瘤分子病理研究院②合作报道了脓毒症通过改变骨髓微环境损害了造血干/祖细胞向免疫活性的浆细胞样树突状细胞的重建，文章发表在Int J Biochem Cell Biol.
2025 Sep;186:106823. doi: 10.1016/j.biocel.2025.106823.
Sepsis impairs immunocompetent plasmacytoid dendritic cell reconstitution from hematopoietic stem/progenitor cell through altered bone marrow environment.
抗CD19外泌体递送系统跨越血脑屏障靶向中枢神经系统淋巴瘤，文章发表在Journal of Nanobiotechnology.
2025 Mar 5;23(1):173. doi: 10.1186/s12951-025-03238-9.
An anti-CD19-exosome delivery system navigates the blood-brain barrier for targeting of central nervous system lymphoma.
苏州大学附属第二医院血液科①与苏州精准医疗②合作报道了以PIM1为靶点治疗弥漫性大b细胞淋巴瘤的天然产物，文章发表在 Annals of Hematology.
2024 Aug;103(8):2905-2915. doi: 10.1007/s00277-024-05670-7.
A promising natural product in diffuse large B-cell lymphoma therapy by targeting PIM1
无锡市人民医院血液科①与苏州精准医疗②合作报道了一例伴有KMT2A::DCP1B融合的慢性中性粒细胞白血病患者，文章发表在International Journal of Laboratory Hematology.
2024 Feb;46(1):165-168. doi: 10.1111/ijlh.14173.
A novel KMT2A::DCP1B rearrangement in chronic neutrophilic leukemia
苏州大学附属第二医院血液科①与苏州精准医疗②合作报道了CMSS1::FLT1在AML患者中的重排导致FLT1信号的激活改变细胞的凋亡和药物敏感性，文章发表在Am J Hematol.
2023 Dec;98(12):E380-E382. doi: 10.1002/ajh.27108.
CMSS1::FLT1 rearrangement leads to ligand-independent activation of FLT1 signaling in acute myeloid leukemia
苏州大学附属儿童医院血液科①与苏州精准医疗②合作报道了世界首例恶性肿瘤中的SNCB基因融合，文章发表在Front. Oncol.
2023 May 12;13:1167143. doi: 10.3389/fonc.2023.1167143.
Intragenic β-synuclein rearrangements in malignancy.
苏州大学附属第二医院神经外科、复旦大学附属华山医院神经外科等①与苏州精准医疗②合作报道了中国家族性脑海绵状血管畸形的分子遗传学特征及临床表现：从新型KRIT1/CCM1突变（c.1119dupT）到整体观点，文章发表在Front. Neurosci.
2023 May 5;17:1184333. doi: 10.3389/fnins.2023.1184333.
Molecular genetic features and clinical manifestations in Chinese familial cerebral cavernous malformation: from a novel KRIT1/CCM1 mutation (c.1119dupT) to an overall view.
苏州大学附属第二医院血液科①与苏州精准医疗②合作报道了弥漫性大B细胞淋巴瘤中的IGH::CD274 (PD-L1)重排及其对治疗的影响，文章发表在EJHaem.
2023 Apr 25;4(2):442-445. doi: 10.1002/jha2.693.
IGH::CD274 (PD-L1) rearrangement in diffuse large B cell lymphoma and its therapeutic implication
海口市人民医院血液科等①与苏州精准医疗科技②合作报道了一例侵袭性急性髓系白血病（AML）伴HNRNPH1::ERG重排，文章发表在Genes Chromosomes Cancer.
2022 Aug;61(8):503-508. doi: 10.1002/gcc.23051.
A novel HNRNPH1::ERG rearrangement in aggressive acute myeloid leukemia.
苏州大学附属儿童医院血液科①与苏州精准医疗科技②合作报道了在缺乏明确预后分级基因改变的儿童B-ALL中高表达白细胞介素3受体α链 (CD123)预示着预后良好。文章发表在Front Oncol.
2021 Mar 16;11:614420. doi: 10.3389/fonc.2021.614420.
High Expression of Interleukin-3 Receptor Alpha Chain (CD123) Predicts Favorable Outcome in Pediatric B-Cell Acute Lymphoblastic Leukemia Lacking Prognosis-Defining Genomic Aberrations.
哈佛大学BWH医院等①与苏州精准医疗科技②合作报道了5q和7q缺失的髓系恶性肿瘤常伴有复杂基因组改变、TP53双等位基因突变以及预后不良。文章发表在Blood Cancer J.
2021 Feb 8;11(2):18. doi: 10.1038/s41408-021-00416-4.
Myeloid malignancies with 5q and 7q deletions are associated with extreme genomic complexity, biallelic TP53 variants, and very poor prognosis.
苏州大学附属第一医院血液科①与苏州精准医疗科技②合作报道了世界首例Ph-like ALL伴STRBP-JAK2基因融合，文章发表在Frontiers in Oncology.
2021 Jan 11;10:611467. doi: 10.3389/fonc.2020.611467.
Identification of STRBP as a Novel JAK2 Fusion Partner Gene in a Young Adult With Philadelphia Chromosome-Like B-Lymphoblastic Leukemia.
无锡市人民医院血液科①与苏州精准医疗科技②合作报道了一例罕见的髓系/淋系肿瘤伴FTL3 重排，文章发表在Br J Haematol.
2020 Oct;191(2):297-301. doi: 10.1111/bjh.16995.
ZBTB44-FLT3 fusion in a patient with a myeloproliferative neoplasm.
哈佛大学BWH医院等①与苏州精准医疗科技②合作报道了髓系肿瘤中IGH重排。文章发表在Haematologica.
2020 Jun;105(6):e315-e317. doi: 10.3324/haematol.2020.246744.
IGH rearrangement in myeloid neoplasms.
南阳市中心医院①、广州医科大学血液科等②与苏州精准医疗科技③合作报道了世界首例AML伴RUNX1-TACC1基因融合，文章发表在Br J Haematol.
2020 Apr;189(2):e52-e56. doi: 10.1111/bjh.16444.
Identification of a novel RUNX1-TACC1 fusion transcript in acute myeloid leukemia.
苏州大学附属第一医院血液科①与苏州精准医疗科技②合作报道了世界首例达沙替尼有效治疗小儿复发B-ALL伴NCOR1-LYN基因融合，文章发表在Front Oncol.
2020 Mar 20;10:359. doi: 10.3389/fonc.2020.00359.
Rapid Molecular Response to Dasatinib in a Pediatric Relapsed Acute Lymphoblastic Leukemia With NCOR1-LYN Fusion.
中国医科大学第一附属医院血液科①等与苏州精准医疗科技②合作报道了一例罕见的髓系/淋系肿瘤伴FGFR1重排合并RUNX1和NOTCH1 突变，文章发表在Front Oncol.
2019 Nov 22;9:1304. doi: 10.3389/fonc.2019.01304.
Myeloid/Lymphoid Neoplasm With FGFR1 Rearrangement Accompanying RUNX1 and NOTCH1 Gene Mutations.
哈佛大学BWH医院①与苏州精准医疗科技②合作报道了急性髓系白血病的继发性改变ZMYM2-FGFR1基因融合。文章发表在Leuk Lymphoma.
2019 Feb;60(2):556-558.doi:10.1080/10428194.2018.1493733.
ZMYM2-FGFR1 fusion as secondary change in acute myeloid leukemia.
哈佛大学Daner-Faber癌症中心等①与苏州精准医疗科技②合作报道了通过单细胞DNA和RNA靶基因测序在CLL中发现LCP1和WNK1突变为新的驱动基因及其功能，文章发表在Genome Res.
2017 Aug;27(8):1300-1311.doi:10.1101/gr.217331.116.
Integrated single-cell genetic and transcriptional analysis suggests novel drivers of chronic lympho-cytic leukemia.
苏州大学附属第二医院血液科①与苏州精准医疗②合作报道了BCL6使DLBCL对HDAC抑制剂产生耐药性，文章发表在 Biochemical Pharmacology.
2024 Sep;227:116466. doi: 10.1016/j.bcp.2024.116466.
BCL6 confers resistance to HDAC inhibitors in DLBCL.
FUS/EWSR1::TFCP2重排骨与软组织肿瘤：融合基因谱系非特异性的证据，文章发表在Virchows Archiv.
2026 Sep 1. doi: 10.1007/s00428-026-04694-w.
FUS/EWSR1::TFCP2-Rearranged Bone and Soft Tissue Tumors: Evidence of Gene Promiscuity.
NOTCH3内部串联重复揭示Notch信号通路的一种新型致癌激活机制，文章发表在Genes Chromosomes Cancer.
2026 Sep;65(9):e70169. doi: 10.1002/gcc.70169.
NOTCH3 Internal Tandem Duplication Defines a Novel Oncogenic Activation Mechanism of Notch Signaling.
中央传导性淋巴管异常患者中的NRAS突变及Gorham-Stout病患者中的PPFIBP1::ROS1融合，文章发表在Human Molecular Genetics.
2026 Jul 28;35(16):ddag070. doi: 10.1093/hmg/ddag070.
NRAS mutation in a central conducting lymphatic anomaly and PPFIBP1::ROS1 fusion in a Gorham-stout disease patient.
RET融合伴侣决定未分化梭形细胞肉瘤的致癌潜能，文章发表在Cancer Biology & Therapy.
2026 Dec 31;27(1):2683190. doi: 10.1080/15384047.2026.2683190.
RET fusion partners dictate oncogenic potential in undifferentiated spindle cell sarcomas.
儿童肉瘤中新型SMARCA4::VEZF1重排，文章发表在Genes Chromosomes Cancer.
2026 May;65(5):e70132. doi: 10.1002/gcc.70132.
Novel SMARCA4::VEZF1 rearrangement in pediatric sarcomas.
分子学确诊小脑毛细胞型星形细胞瘤患者发生的脊髓具有毛细胞样特征的高级别星形细胞瘤，文章发表在Neuro-oncology Advances.
2026 Apr 20;8(1):vdag104. doi: 10.1093/noajnl/vdag104.
Spinal high-grade astrocytoma with piloid features arising in a patient with molecularly confirmed cerebellar pilocytic astrocytoma.
伴BRAF V600E突变的滑膜肉瘤：病例报告及文献综述，文章发表在Genes Chromosomes Cancer.
2026 May;65(5):e70128. doi: 10.1002/gcc.70128.
Synovial Sarcoma with BRAF V600E Mutation: A Case Report and Literature Review.
苏州大学附属第一医院普外科等①与苏州赛默医学检验实验室②合作报道了甲状腺乳头状癌中新型SORBS2::BRAF融合，文章发表在Virchows Archiv.
2026 May;488(5):1175-1181. doi: 10.1007/s00428-026-04447-9.
Unveiling a New SORBS2::BRAF Fusion in Papillary Thyroid Carcinoma: Insights from Molecular Diagnostics.
南京医科大学第一附属医院病理科等①与苏州大学一苏州精准肿瘤分子病理研究院②合作报道了青少年高度侵袭性腹膜间皮瘤中发现新型EWSR1::TEAD3融合基因，文章发表在Genes Chromosomes Cancer.
2026 Feb;65(2):e70113. doi: 10.1002/gcc.70113.
Novel EWSR1::TEAD3 Fusion in an Adolescent with a Highly Aggressive Peritoneal Mesothelioma.
湖南省儿童医院小儿心外科等①与苏州大学一苏州精准肿瘤分子病理研究院②合作报道了DICER1综合征中的突变-组织特异性:来自家族性胸膜肺母细胞瘤的见解及泛肿瘤热点分析，文章发表在Pathology.
2026 Apr;58(3):360-364. doi: 10.1016/j.pathol.2025.10.012.
Mutation-Tissue Specificity in DICER1 Syndrome: Insights from Familial PPB and a Pan-Tumor Hotspot Analysis.
苏州赛默医学检验实验室自研报道了一篇增强肿瘤中EGFRvIII的检测:一项基于分裂读取和测序深度的DNA测序方法的比较研究，文章发表在Journal of Molecular Diagnostics.
2026 Feb;28(2):179-186. doi: 10.1016/j.jmoldx.2025.11.002.
Enhanced Detection of EGFRvIII in Tumors: A Comparative Study of Split Read and Read Depth-Based NGS Approaches.
佛山市中医院病理科等①与苏州大学一苏州精准肿瘤分子病理研究院②合作报道了滑膜肉瘤荧光原位杂交假阴性:一例因罕见基因组插入导致SS18:.SSX2融合漏诊的病例，文章发表在Pathology.
2026 Apr;58(3):357-360. doi: 10.1016/j.pathol.2025.09.011.
False-Negative FISH in Synovial Sarcoma: A Case of Missed SS18::SSX2 Fusion Due to Rare Genomic Insertion.
苏州大学附属儿童医院普外科等①与苏州大学一苏州精准肿瘤分子病理研究院②合作报道了一例病例报告:FGFR1突变和染色体广泛丢失驱动低级别胶质瘤恶性转化，文章发表在Frontiers in Oncology.
2025 Nov 14;15:1694881. doi: 10.3389/fonc.2025.1694881.
Case Report: FGFR1 mutation and massive chromosome loss drive malignant transformation of low-grade gliomas.
中山大学附属第一医院病理科等①与苏州大学一苏州精准肿瘤分子病理研究院②合作报道了一例携带新型CHD9::BEND2融合基因的儿童低度恶性鼻窦间叶组织瘤，文章发表在Virchows Archiv.
2025 Oct 20. doi: 10.1007/s00428-025-04307-y.
A pediatric low-grade sinonasal mesenchymal tumor harboring a novel CHD9::BEND2 fusion.
佛山中医院病理科等①与苏州大学一苏州精准肿瘤分子病理研究院②合作报道了一例伴LDB1::KMT2A融合的梭形细胞肉瘤的病例报告，文章发表在Genes Chromosomes Cancer.
2025 Sep;64(9):e70084. doi: 10.1002/gcc.70084.
LDB1::KMT2A Fusion in a Spindle-Cell Sarcoma: A Case Report.
中南大学湘雅医院肿瘤科等①与苏州大学一苏州精准肿瘤分子病理研究院②合作报道了梭形细胞肉瘤中的一种新型ACVR2A::RAF1融合，文章发表在Genes Chromosomes Cancer.
2025 Feb;64(2):e70033. doi: 10.1002/gcc.70033.
A Novel ACVR2A::RAF1 Fusion in Spindle Cell Sarcoma.
脱氧核糖的代谢同位素标记实现用于核酸修饰谱分析的双中性丢失扫描，文章发表在Nucleic Acids Research.
2026 Feb 24;54(5):gkag155. doi: 10.1093/nar/gkag155.
Metabolic isotopic labeling of (deoxy)ribose enables dual neutral loss scanning for profiling nucleic acid modifications.
仑伐替尼联合依维莫司通过上调ITGB4表达协同抑制神经内分泌肿瘤，文章发表在Endocrine-related cancer.
2026 Jan 7;33(1):e250233. doi: 10.1530/ERC-25-0233.
Lenvatinib and everolimus synergistically inhibit neuroendocrine neoplasms by upregulating ITGB4 expression.
不同免疫治疗对肝细胞癌生存获益的影响：一项聚焦年龄、性别、病因及肿瘤负荷的Meta分析，文章发表在Frontiers in immunology.
2025 Dec 10;16:1713151. doi: 10.3389/fimmu.2025.1713151.
Survival benefits of different immunotherapies for hepatocellular carcinoma: a meta-analysis highlighting age, gender, etiology, and tumor burden.
中山大学附属第一医院放射介入科等①与苏州大学一苏州精准肿瘤分子病理研究院②合作报道了一篇揭示IncRNA PIG13-DT在肝细胞癌进展中的致癌作用，文章发表在Cancer Biology & Therapy.
2025 Dec 31;26(1):2567797. doi: 10.1080/15384047.2025.2567797.
Unveiling the oncogenic role of lncRNA PIG13-DT in hepatocellular carcinoma progression.
苏州大学附属第四医院胸外科等①与苏州大学一苏州精准肿瘤分子病理研究院②合作报道了Decursin通过协同调控细胞周期阻滞、凋亡激活与促癌蛋白降解抑制食管鳞状细胞癌进展，文章发表在International Journal of Molecular Sciences.
2025 Jun 4;26(11):5391. doi: 10.3390/ijms26115391.
Decursin Suppresses Esophageal Squamous Cell Carcinoma Progression via Orchestrated Cell Cycle Deceleration, Apop-totic Activation, and Oncoprotein Degradation.
哈尔滨医科大学等①与苏州赛默医学检验实验室②合作报道了RPL22L1通过调控DUSP6-ERK轴促进宫颈癌的恶性进展，文章发表在Journal of Translational Medicine.
2025 Feb 28;23(1):244. doi: 10.1186/s12967-025-06249-0.
RPL22L1 fosters malignant features of cervical cancer via the modulation of DUSP6-ERK axis.
苏州大学附属第一医院妇产科等①与苏州大学一苏州精准肿瘤分子病理研究院②合作报道了子宫内膜癌中葡萄糖代谢相关基因特征的识别与验证，文章发表在BMC Cancer.
2025 Jan 7;25(1):30. doi: 10.1186/s12885-024-13418-9.
Identification and validation of glucose metabolism-related gene signature in endometrial cancer.
苏州大学附属第四医院肿瘤科等①与苏州赛默医学检验实验室②合作报道了替莫唑胺通过激活ERK信号通路促进MGMT转录从而导致恶性黑色素瘤的化疗耐药，文章发表在Joumal of cellular and molecular medicine.
2025 Feb;29(3):e70380. doi: 10.1111/jcmm.70380.
Temozolomide-Promoted MGMT Transcription Contributes to Chemoresistance by Activating the ERK Signalling Pathway in Malignant Melanoma.
山西大学生物技术研究所等①与苏州赛默医学检验实验室②合作报道了黑豆皮花青素通过调控JAK2/STAT3通路促进肝细胞癌细胞凋亡，文章发表在International Journal Of Molecular Sciences.
2025 Jan 26;26(3):1070. doi: 10.3390/ijms26031070.
Anthocyanins in Black Soybean Coats Promote Apoptosis in Hepatocellular Carcinoma Cells by Regulating the JAK2/STAT3 Pathway.
苏州大学附属第一医院普外科等①与苏州大学一苏州精准肿瘤分子病理研究院②合作报道了瘦素通过抑制CPT1B增强结直肠癌细胞的化疗敏感性，文章发表在Journal of Gatroinstestinal Oncology.
2024 Dec 31;15(6):2507-2520. doi: 10.21037/jgo-2024-950. Epub 2024 Dec 28.
Leptin increases chemosensitivity by inhibiting CPT1B in colorectal cancer cells.
苏州大学附属第一医院妇产科等①与苏州赛默医学检验实验室②合作报道了从遗传变异视角揭示子宫内膜癌亚型的潜在药物靶点，文章发表在Scientific reports.
2024 Nov 15;14(1):28180. doi: 10.1038/s41598-024-78689-5.
Genetic variation perspective reveals potential drug targetsfor subtypes ofendometrial cancer.
苏州大学附属第一医院普外科等①与苏州大学一苏州精准肿瘤分子病理研究院②合作报道了生酮饮食通过AMOT-YAP/TAZ轴调节肿瘤相关中性粒细胞极化以抑制结直肠癌进展，文章发表在Pharmacological Research.
2024 Dec;210:107494. doi: 10.1016/j.phrs.2024.107494. Epub 2024 Nov 5.
The Ketogenic Diet Modulates Tumor-Associated Neutrophil Polarization via the AMOT-YAP/TAZ Axis to Inhibit Colorectal Cancer Progression.
南通大学附属医院甲乳外科、嘉善县第一人民医院甲乳外科、浦东新区人民医院普外科①与苏州精准医疗②合作报道了两例ETV6-NTRK3重排乳头状甲状腺癌的临床病理特征：病例报告，文章发表在Front. Oncol.
2024 May 28;14:1332522. doi: 10.3389/fonc.2024.1332522.
Clinicopathological features of two cases of ETV6-NTRK3 rearranged papillary thyroid carcinoma: a case report
苏州大学附属第一医院妇产科①与苏州精准医疗②合作报道了胚系 CHEK1c.613+2T>C 突变导致剪接错误和家族性肿瘤，文章发表在Frontiers in Oncology
2024 Apr 15;14:1380093. doi: 10.3389/fonc.2024.1380093.
Case report: A germline CHEK1 c.613 + 2T>C leads to a splicing error in a family with multiple cancer patients
中南大学湘雅医院肿瘤科①与苏州精准医疗②合作报道了一例MDM2和HMGA2扩增的去分化脂肪肉瘤中发现一种新的HMGA2::KITLG融合，文章发表在Genes Chromosomes Cancer.
2024 Jan;63(1):e23200. doi: 10.1002/gcc.23200.
A novel HMGA2::KITLG fusion in a dedifferentiated liposarcoma with amplification of MDM2 and HMGA2.
苏州大学附属第二医院神经外科①与苏州精准医疗②合作报道了世界首例毛细胞型星形细胞瘤中的RIN2::BRAF融合，文章发表在Virchows Archiv.
2023 Feb;482(2):451. doi: 10.1007/s00428-022-03485-3.
Rare adult pilocytic astrocytoma of the septum pellucidum with novel RIN2::BRAF fusion
苏州大学附属第二医院神经外科与苏州精准医疗合作报道了一例胚胎发育不良性神经上皮肿瘤中新型LHFPL3::NTRK2融合，文章发表在Front. Oncol.
2022 Dec 1;12:1064817. doi: 10.3389/fonc.2022.1064817.
Case Report: A novel LHFPL3::NTRK2 fusion in dysembryoplastic neuroepithelial tumor.
苏州大学第二附属医院甲乳外科等①与苏州精准医疗科技②合作报道了应用二代测序技术对甲状腺乳头状癌突变基因谱及临床特征相关性的研究，文章发表在中华实验外科杂志。
2022年7月第39卷，doi：10.3760/cma.j.cn421213-20220418-00290。
应用二代测序技术对甲状腺乳头状癌突变基因谱及临床特征相关性的研究
苏州大学附属第二医院神经外科①与苏州精准医疗科技②合作报道了一例具有骨肉瘤成分的胶质瘤肉病例报道及文献复习，文章发表在Pathology - Research and Practice.
2022 Apr;232:153837. doi: 10.1016/j.prp.2022.153837.
Gliosarcoma with osteosarcomatous component: A case report and short review illustration.
苏州市儿童医院血液科与苏州精准医疗科技合作报道了一例特殊的含KIT病理突变的卵巢生殖细胞肿瘤/肥大细胞增多症。文章发表在Genes Chromosomes Cancer.
2022 Jan;61(1):50-54. doi: 10.1002/gcc.23000.
Ovarian germ cell tumor/mastocytosis with KIT mutation: A unique clinicopathological entity.
中国医科大学附属盛京医院等①与苏州精准医疗科技②合作报道了RPL41通过下调ATF4提高视网膜母细胞瘤对化疗药物敏感性，文章发表在J CellPhysiol.
2021 Mar;236(3):2214-2225. doi: 10.1002/jcp.30010.
RPL41 sensitizes retinoblastoma cells to chemotherapeutic drugs via ATF4 degradation.
哈佛大学BWH医院①与苏州精准医疗科技②合作报道了世界首例多形性汗腺癌（PSGC）伴有MYB融合，文章发表在Histopathology.
2020 Apr;76(5):779-781. doi: 10.1111/his.14025.
Polymorphous sweat gland carcinoma found to have MYB rearrangement.
苏州大学附属儿童医院①与苏州精准医疗科技②合作报道了世界第二例肾癌伴EWSR1-TFE3融合，文章发表在Genes Chromosomes Cancer.
2020 May;59(5):325-329. doi: 10.1002/gcc.22830.
A renal cell carcinoma with EWSR1-TFE3 fusion gene.
苏州大学附属儿童医院血液科等①与苏州精准医疗科技②合作报道了PROTAC溴化腺素抑制剂ARV-825在神经母细胞瘤中的抗肿瘤活性并阐述其分子机制。文章发表在Front Oncol.
2020 Nov 26;10:574525. doi: 10.3389/fonc.2020.574525.
PROTAC Bromodomain Inhibitor ARV-825 Displays Anti-Tumor Activity in Neuroblastoma by Repressing Expression of MYCN or c-Myc.
哈佛大学BWH医院①与苏州精准医疗科技②合作报道RCC2过表达通过激活Rac1从而改变肿瘤细胞的凋亡和药物敏感性。文章发表在BMC Cancer.
2018 Jan 10;18(1):67. doi: 10.1186/s12885-017-3908-y.
RCC2 over-expression in tumor cells alters apoptosis and drug sensitivity by regulating Rac1 activation.
中国医科大学附属盛京医院眼科①与苏州精准医疗科技②合作报道了小分子肽RPL41通过降低ATF4减弱缺氧诱导视网膜病变小鼠的视网膜新生血管形成。文章发表在Exp Cell Res.
2018 Aug 15;369(2):243-250. doi: 10.1016/j.yexcr.2018.05.027.
Mini-peptide RPL41 attenuated retinal neovascularization by inducing degradation of ATF4 in oxygen-induced retinopathy mice.
中南大学湘雅医院肿瘤科①与苏州精准医疗②合作报道了第二例EGFL7::FOSB融合相关的假肌源性血管内皮瘤表现出不同的临床特征，文章发表在Histopathology.
2024 Mar;84(4):708-712. doi: 10.1111/his.15108.
Diverse clinical presentations of pseudomyogenic hemangioendothelioma associated with EGFL7::FOSB fusion: a second case
苏州大学附属第一医院神经外科①与苏州精准医疗②合作报道了胚系CHEK2突变与巨细胞胶质母细胞瘤相关的病例，文章发表在Frontiers in Oncology.
2024 Oct 1;14:1361928. doi: 10.3389/fonc.2024.1361928.
Case report: Germline CHEK2 mutation is associated with a giant cell glioblastoma.
苏州市工业园区启月街288号紫金东方商务广场C幢603.608室
苏州市工业园区星湖街218号生物医药产业园B2栋701.703单元
苏州市工业园区启月街288号
紫金东方商务广场C幢603.608室
苏州市工业园区星湖街218号
生物医药产业园B2栋701.703单元