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哈佛大学BWH医院等①与苏州精准医疗科技②合作报道了5q和7q缺失的髓系恶性肿瘤常伴有复杂基因组改变、TP53双等位基因突变以及预后不良。文章发表在Blood Cancer J.

Myeloid malignancies with 5q and 7q deletions are associated with extreme genomic complexity, biallelic TP53 variants, and very poor prognosis.